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Scientist - Systems Biology

OVERALL RESPONSIBILITY:

To develop computational methods for studying complex cellular networks to elucidate their operating principles and to enable their rational re-design. Working in close collaborations with experimental biologists to design predictive and multiscale models enabling the study of metabolic pathways and target drugs.

KEY TASKS AND RESPONSIBILITIES:

  • Work both independently and collaboratively with research and development scientists to perform computational and statistical analysis of drug pharmacokinetic studies using in-vitro and in-vivo data.
  • Utilize metabolic modeling together with phenotypic profiling and flux measurements to generate a systems computational model of metabolic processes. The model is ultimately intended to help with rational drug design for various diseases.
  • Develop, acquire, and validate software and scripts for computational flux models.

SKILLS AND ATTRIBUTES:

  • Prior experience in flux balance analysis and handling of metabolic databases and measurements is a requirement.
  • Integration of data from many different biological components to develop models for metabolic pathways.
  • Basic background in biology.
  • Expertise with MATLAB/R, python (or comparable scripting language).
  • Ability to work in a highly collaborative and intellectually challenging environment, including excellent oral and written communication skills, to conduct both self-directed and guided computational research.

EDUCATION AND EXPERIENCE:

  • Ph.D. in Computational Biology, Systems Biology, Bioinformatics, Computer Ccience, Engineering, Statistics, Physics, Mathematics or a related field.

Please send a cover letter and CV to: Careers@axcellahealth.com